| Guffie, Kentucky | |
| Settlement Type: | Unincorporated community |
| Pushpin Map: | USA Kentucky#USA |
| Pushpin Label: | Guffie |
| Pushpin Label Position: | bottom |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | Kentucky |
| Subdivision Type2: | County |
| Subdivision Name2: | McLean |
| Unit Pref: | Imperial |
| Population As Of: | 2000 |
| Population Density Km2: | auto |
| Timezone: | Central (CST) |
| Utc Offset: | -6 |
| Timezone Dst: | CDT |
| Utc Offset Dst: | -5 |
| Elevation Ft: | 436 |
| Coordinates: | 37.6042°N -87.2544°W |
| Postal Code Type: | ZIP codes |
| Blank Name: | FIPS code |
| Blank1 Name: | GNIS feature ID |
| Blank1 Info: | 508145 |
Guffie is an unincorporated community located in McLean County, Kentucky, United States. It was also known as Littles Crossroads.
In 2017 Guffie Lake (operated by the local fish and game) had a catastrophic Dam breach. Resulting in the lake completely draining. The cause is unknown at this time and repairs to the Dam have not yet taken place. No injuries were reported.