| Guaynabo River | |
| Pushpin Map: | USA Puerto Rico |
| Subdivision Type1: | Commonwealth |
| Subdivision Name1: | Puerto Rico |
| Subdivision Type2: | Municipality |
| Subdivision Name2: | Guaynabo |
| Source1 Elevation: | 46 ft |
The Guaynabo River (Spanish; Castilian: Río Guaynabo) is a river of Guaynabo, Puerto Rico.
crosses the Frailes Creek tributary