The Liga Nacional de Fútbol de Guatemala Apertura 2007 is the 88th season of the Liga Nacional de Fútbol de Guatemala, Guatemala's premier football league. It began on July 28 and finished on December 15.
Mictlán was relegated at the end of the 2006–07 season and was replaced by Malacateco who was promoted from the Primera División.
| Pos | Player | Team | Goals |
|---|---|---|---|
| 1 | Adrián Apellaniz | Jalapa | 14 |
| 2 | Selvin Motta | Zacapa | 12 |
| 3 |  Jorge Dos Santos | Jalapa | 10 |
| 4 | Tránsito Montepeque | Comunicaciones | 8 |
| 5 | Guillermo Ramírez | Municipal | 7 |
| Mario Rodríguez | Municipal | 7 |
Jalapa as tournament champion qualified to the 2008–09 CONCACAF Champions League.
There is no relegation after the Apertura.