| Official Name: | Guasdualito |
| Pushpin Map: | Venezuela Apure#Venezuela |
| Subdivision Type: | Country |
| Subdivision Type1: | State |
| Subdivision Type2: | Municipality |
| Subdivision Name: | Venezuela |
| Subdivision Name1: | Apure |
| Subdivision Name2: | Páez Municipality |
| Established Title: | Founded |
| Established Date: | 1770/1 |
| Population Total: | 105,000 |
| Timezone: | VET |
| Utc Offset: | -4 |
| Coordinates: | 7.2467°N -70.7292°W |
| Elevation M: | 125 |
| Population Blank1 Title: | Demonym |
| Population Blank1: | Guasdualiteño/a |
| Area Code: | 0278 |
| Postal Code Type: | Postal code |
| Postal Code: | 5063 |
| Blank Name: | Climate |
| Blank Info: | Aw |
Guasdualito is a city and episcopal see in the landlocked Apure State, in southern Venezuela.
The city is the capital of Páez Municipality, in the Distrito Especial Alto Apure. It has an important location on the border between Venezuela and the city of Arauca in Colombia for commerce, as well as being the main petroleum center in the region.
It has a population of approximately 100,000 inhabitants per 2014.
Guasdualito has a tropical savanna climate (Köppen: Aw),[1] characterized by consistently hot temperatures and distinct wet and dry seasons. Guasdualito experiences a wet season from April to November, with the wettest months being May, June, and July. The dry season lasts from December to March. February to April are the hottest months, with average high temperatures around, and the coolest period is from June to August, with average highs around .
The Our Lady of Mount Carmel Cathedral (Catedral Nuestra Señora del Carmen) is dedicated to the Virgin of Mercy and is the cathedral episcopal see of the Roman Catholic Diocese of Guasdualito since December 2015.