| Guanipa River | |
| Mouth Location: | Gulf of Paria |
| Mouth Coordinates: | 10.0438°N -62.4475°W |
| Pushpin Map: | Venezuela |
| Pushpin Map Relief: | 1 |
| Mapframe: | yes |
| Subdivision Type1: | Country |
| Subdivision Name1: | Venezuela |
| Length Km: | 340 |
| Discharge1 Avg: | 600cuft/s |
| Basin Size Mi2: | 1100 |
| Basin Size Ref: | [1] |
Guanipa River is a river of north-eastern Venezuela. It flows into the Gulf of Paria.