| Official Name: | Guamote |
| Settlement Type: | Town |
| Total Type: | Town |
| Pushpin Map: | Ecuador |
| Mapsize: | 200px |
| Subdivision Type: | Country |
| Subdivision Name: |  Ecuador |
| Subdivision Type1: | Province |
| Subdivision Type2: | Canton |
| Subdivision Name2: | Guamote Canton |
| Leader Title: | Mayor |
| Leader Name: | Segundo Miguel Marcatoma Lema |
| Area Total Km2: | 2.44 |
| Population Footnotes: | [1] |
| Population As Of: | 2022 census |
| Population Total: | 3076 |
| Population Density Km2: | auto |
| Timezone: | ECT |
| Coordinates: | -1.9333°N -78.7167°W |
Guamote is a town in the Chimborazo Province, Ecuador. It is the seat of the Guamote Canton.
Guamote is located on Ecuador Highway 35, between Riobamba and Alausí. Ecuador Highway 46 branches in Guamote to the east and connects it with Macas, crossing Sangay National Park.