| Guajará River | |
| Pushpin Map: | Brazil |
| River System: | Amazon River |
| Source1 Location: | Pará state |
| Mouth Location: | Amazon River |
| Mouth Coordinates: | -1.7734°N -52.9918°W |
| Subdivision Type1: | Country |
| Subdivision Name1: | Brazil |
The Guajará River (Portuguese: Rio Guajará) is a tributary of the Amazon River in the state of Pará, Brazil.
The river runs through the Verde para Sempre Extractive Reserve, a sustainable use conservation unit created in 2004, before discharging into the Amazon.