| Guagno | |
| Commune Status: | Commune |
| Arrondissement: | Ajaccio |
| Canton: | Sevi-Sorru-Cinarca |
| Insee: | 2A131 |
| Postal Code: | 20160 |
| Mayor: | Paul-Joseph Colonna[1] |
| Term: | 2020 - 2026 |
| Coordinates: | 42.1694°N 8.9492°W |
| Elevation M: | 800 |
| Elevation Min M: | 491 |
| Elevation Max M: | 2418 |
| Area Km2: | 42.72 |
Guagno is a commune in the Corse-du-Sud department in France on the island of Corsica.
The river Guagno, also called the Fiume Grosso, flows through the commune from east to west. It is a tributary of the Liamone.