| Official Name: | Guadalupe |
| Settlement Type: | Municipality |
| Pushpin Map: | Brazil |
| Pushpin Map Caption: | Location in Brazil |
| Coordinates: | -6.7869°N -43.5689°W |
| Subdivision Type: | Country |
| Subdivision Name: | Brazil |
| Subdivision Type1: | Region |
| Subdivision Name1: | Northeast |
| Subdivision Type2: | State |
| Subdivision Name2: | Piauí |
| Subdivision Type3: | Mesoregion |
| Subdivision Type4: | Microregion |
| Subdivision Type5: | Metrop. region |
| Leader Title: | Mayor |
| Elevation M: | 177 |
| Population Total: | 10,497 |
| Population As Of: | 2020 [1] |
| Population Density Km2: | auto |
| Timezone1: | BRT |
| Utc Offset1: | -3 |
| Postal Code Type: | Postal code |
| Area Code Type: | Area code |
Guadalupe is a municipality of the Brazilian state of Piaui. It is located in latitude 06° 47' 13" south and longitude 43° 34' 09" west, with an elevation of 177 meters.
The Boa Esperança Hydroelectric Power Plant is in Guadalupe, and provides electricity to the state of Piauí.