| Image Coa: | Wappen Großweitzschen.jpg |
| Coordinates: | 51.1667°N 16°W |
| Image Plan: | Großweitzschen in FG.png |
| State: | Sachsen |
| District: | Mittelsachsen |
| Elevation: | 239 |
| Area: | 44.52 |
| Postal Code: | 04720 |
| Area Code: | 0 34 31 |
| Licence: | FG |
| Gemeindeschlüssel: | 14522220 |
| Divisions: | 24 |
| Website: | www.grossweitzschen.de |
| Mayor: | Jörg Burkert[1] |
| Leader Term: | 2018 - 25 |
| Party: | Independent |
Großweitzschen is a municipality in the district of Mittelsachsen, in Saxony, Germany.