| Great Cacapon | |
| Settlement Type: | Census-designated place (CDP) |
| Mapsize: | 260px |
| Subdivision Type: | Country |
| Subdivision Name: | United States |
| Subdivision Type1: | State |
| Subdivision Name1: | West Virginia |
| Subdivision Type2: | County |
| Subdivision Name2: | Morgan |
| Area Footnotes: | [1] |
| Area Total Sq Mi: | 0.857 |
| Area Land Sq Mi: | 0.857 |
| Area Water Sq Mi: | 0 |
| Population As Of: | 2010 |
| Population Footnotes: | [2] |
| Population Total: | 386 |
| Population Density Sq Mi: | auto |
| Timezone: | Eastern (EST) |
| Utc Offset: | -5 |
| Timezone Dst: | EDT |
| Utc Offset Dst: | -4 |
| Elevation Ft: | 532 |
| Coordinates: | 39.6144°N -78.2858°W |
| Postal Code Type: | ZIP codes |
| Blank Name: | FIPS code |
| Blank1 Name: | GNIS feature ID |
| Blank1 Info: | 2586817 |
Great Cacapon is a census-designated place (CDP) in Morgan County in the U.S. state of West Virginia's Eastern Panhandle. As of the 2010 census, its population was 386.
Great Cacapon takes its name from the Cacapon River (from the Native American meaning "medicine water") which empties into the Potomac River to the town's east. It was originally known as Cacapon Depot on the Baltimore and Ohio Railroad mainline when a post office was established here in 1848. In 1876, its name was changed to Great Cacapon to differentiate it from Little Cacapon which was also on the B&O mainline. It lies four miles down Cacapon Mountain from the Panorama Overlook along Cacapon Road (West Virginia Route 9) west of Berkeley Springs.