| Official Name: | Grande-Saline |
| Native Name: | Grann Salin |
| Settlement Type: | Commune |
| Pushpin Map: | Haiti |
| Pushpin Map Caption: | Location in Haiti |
| Subdivision Type: | Country |
| Subdivision Name: | Haiti |
| Subdivision Type1: | Department |
| Subdivision Name1: | Artibonite |
| Subdivision Type2: | Arrondissement |
| Subdivision Name2: | Dessalines |
| Area Total Km2: | 51.97 |
| Population As Of: | 2015 |
| Population Footnotes: | [1] |
| Population Total: | 23236 |
| Population Density Km2: | auto |
| Timezone: | EST |
| Utc Offset: | −05:00 |
| Timezone Dst: | EDT |
| Utc Offset Dst: | −04:00 |
| Coordinates: | 19.25°N -72.7833°W |
| Elevation M: | 0 |
| Postal Code Type: | Postal code |
| Postal Code: | HT 4430 |
Grande-Saline (pronounced as /fr/; ht|Grann Salin) is a commune in the Dessalines Arrondissement in the Artibonite department of Haiti.