Grahame Hardie Explained

Honorific Prefix:	Professor
Field:	Biochemistry
Known For:	Discovery of AMP-activated protein kinase
Workplaces:	University of Dundee
Thesis Title:	Cereal Carbohydrases
Thesis Url:	http://hdl.handle.net/10399/1903
Thesis Year:	1974
Birth Date:	5 April 1950

David Grahame Hardie (born 1950) is a Scottish biochemist, and Professor of Cellular Signalling, at the School of Life Sciences, University of Dundee.^[1]

Career and research

He was a member of the Faculty of 1000.^[2] He is known for the discovery of AMP-activated protein kinase (AMPK).^[3]

Publications

• of AMP-activated protein kinase by natural and synthetic activators", Acta Pharmaceutica Sinica B (2016) 6, (1–19)
• "AMP-activated protein kinase: a cellular energy sensor with a key role in metabolic disorders and in cancer", Biochemical Society Transactions (2011) 39, (1–13)
• Book: https://books.google.com/books?id=Hz_2HV1GWfMC&pg=PA53. Analysis of signal transduction pathways using protein serine - threonine phosphate inhibitors. Protein phosphorylation: a practical approach. D. Grahame Hardie. Oxford University Press. 1999. 978-0-19-963729-4.
• Book: Biochemical messengers: hormones, neurotransmitters, and growth factors. Springer. 1991. 978-0-412-30350-0.

External links

• http://www.biomedcentral.com/authors/profiles/grahamehardie
• https://web.archive.org/web/20120426072341/http://mediacentral.cshl.edu/Symposium76/Symposium76/Interviews/Entries/2011/6/5_Grahame_Hardie.html
• http://homecomingscotlandblog.blogspot.com/2008/10/professor-grahame-hardie-frs-frse.html

Notes and References

1. Web site: Professor Grahame Hardie FRS, FRSE, FMedSci. 2013-08-30.
2. Web site: David Grahame Hardie - F1000Prime.
3. Winder WW, Hardie DG . AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetes . The American Journal of Physiology . 277 . 1 . E1-10 . July 1999 . 10409121 . 10.1152/ajpendo.1999.277.1.E1 .