| Western Region Premier | Title | Took office | Left office | Party | Notes | |
|---|---|---|---|---|---|---|
| Obafemi Awolowo | Premier | 1954 | 1959 | |||
| Samuel Ladoke Akintola | Premier | 1960 | May 1962 | |||
| Senator (Doctor) Moses Majekodunmi | Administrator | 29 June 1962 | December 1962 | Appointed during political emergency | ||
| Samuel Ladoke Akintola | Premier | 1 January 1963 | 15 January 1966 | |||
| Western Region Governor | ||||||
| Sir John Dalzell Rankine | Governor | 1 October 1954 | July 1960 | |||
| Sir Adesoji Aderemi | Governor | July 1960 | December 1962 | |||
| Chief Joseph Odeleye Fadahunsi | Governor | December 1962 | 15 January 1966 | |||
| Lt. Colonel Adekunle Fajuyi | Governor | 15 January 1966 | 29 July 1966 | (Military) | ||
| Robert Adeyinka Adebayo | Governor | 4 August 1966 | 27 May 1967 | (Military) | Continued as governor of Western State | |
| Western State Governor | Excludes Lagos, split off as a separate state | |||||
| Robert Adeyinka Adebayo | Governor | 28 May 1967 | 1 April 1971 | (Military) | ||
| Brig. Gen. Christopher Oluwole Rotimi | Governor | 1 April 1971 | July 1975 | (Military) | ||
| Akintunde Aduwo | Governor | 30 July 1975 | 30 August 1975 | (Military) | ||
| David Jemibewon | Governor | 30 August 1975 | March 1976 | (Military) |