The Government of the Federation of Rhodesia and Nyasaland was established in 1953 and ran the Federation until its dissolution at the end of 1963. The members of the government were accountable to, and drawn from, the unicameral Federal Parliament.
| Office | Minister | Date appointed | |
|---|---|---|---|
| Prime Minister | Godfrey Martin Huggins | 7 September 1953 | |
| Minister of External Affairs and Defence | |||
| Minister of Finance | |||
| Minister of Transport and Development | Roy Welensky | 7 September 1953 | |
| Minister of Internal Affairs | Malcolm Palliser Barrow | 7 September 1953 |
| Office | Minister | Date appointed | |
|---|---|---|---|
| Prime Minister | Godfrey Martin Huggins | 18 December 1953 - 2 November 1956 | |
| Minister of External Affairs | |||
| Minister of Defence | |||
| Minister of Transport | Roy Welensky | 18 December 1953 - 12 February 1954 | |
| Minister of Communications | |||
| Minister of Transport and Communications | Roy Welensky | 12 February 1954 | |
| Minister of Posts | |||
| Minister of Finance | Donald MacIntyre | 18 December 1953 | |
| Minister of Agriculture | John Moore Caldicott | 18 December 1953 | |
| Minister of Health | |||
| Minister of Internal Affairs | Malcolm Palliser Barrow | 18 December 1953 – 12 February 1954 | |
| Minister of Home Affairs | Malcolm Palliser Barrow | 12 February 1954 – 7 June 1955 | |
| Frank Stephen Owen | 7 June 1955 | ||
| Minister of Commerce and Industry | Malcolm Palliser Barrow | 12 February 1954 | |
| Minister of Power | 7 April 1955 | ||
| Minister of Education | Julian MacDonald Greenfield | 12 February 1954 |
| Office | Minister | Date appointed | |
|---|---|---|---|
| Prime Minister | Sir Roy Welensky | 2 November 1956 - 31 December 1963 | |
| Minister of External Affairs | |||
| Minister of Defence | 2 November 1956 – 12 June 1959 | ||
| John Moore Caldicott | 12 June 1959 – 7 May 1962 | ||
| Sir Malcolm Palliser Barrow | 7 May 1962 – 31 December 1963 | ||
| Deputy Prime Minister | 7 May 1962 – 31 December 1963 | ||
| Minister of Home Affairs | Sir Malcolm Palliser Barrow | 2 November 1956 – 7 May 1962 | |
| Julian Greenfield | 7 May 1962 – 31 December 1963 | ||
| Minister of Power | Sir Malcolm Palliser Barrow | 2 November 1956 – 31 December 1963 | |
| Minister of Finance | Donald MacIntyre | 2 November 1956 – 3 September 1962 | |
| John Moore Caldicott | 3 September 1962 – 31 December 1963 | ||
| Minister of Posts | Donald MacIntyre | 2 November 1956 – 11 December 1958 | |
| Frank Stephen Owen | 11 December 1958 – 31 December 1963 | ||
| Minister of Public Service | John Moore Caldicott | 2 November 1956 – 3 September 1962 | |
| John Philip Gold Duncan | 3 September 1962 – 31 December 1963 | ||
| Minister of Agriculture | John Moore Caldicott | 2 November 1956 – 11 December 1958 | |
| John Cranmer Graylin | 11 December 1958 – 1 September 1963 | ||
| James Arthur Clark | 1 September 1963 – 31 December 1963 | ||
| Minister of Health | John Moore Caldicott | 2 November 1956 – 11 December 1958 | |
| Benjamin Disraeli Goldberg | 11 December 1958 – 31 December 1963 | ||
| Minister of Economic Affairs | John Moore Caldicott | 11 December 1958 – 7 May 1962 | |
| Sir Malcolm Palliser Barrow | 7 May 1962 – 31 December 1963 | ||
| Minister of Law | Julian MacDonald Greenfield | 2 November 1956 – 31 December 1963 | |
| Minister of Education | 2 November 1956 – 11 December 1958 | ||
| Benjamin Disraeli Goldberg | 11 December 1958 – 7 May 1962 | ||
| John Philip Gold Duncan | 7 May 1962 – 31 December 1963 | ||
| Minister of Commerce and Industry | Frank Stephen Owen | 2 November 1956 – 7 May 1962 | |
| James Arthur Clark | 7 May 1962 – 31 December 1963 | ||
| Minister of Transport and Works | William Hives Eastwood | 2 November 1956 – 11 December 1958 | |
| Minister of Transport | William Hives Eastwood | 11 December 1958 – 7 May 1962 | |
| Frank Stephen Owen | 7 May 1962 – 31 December 1963 | ||
| Minister of Works | George Wellington Rex L'Ange | 11 December 1958 – 31 December 1963 |
| Office | Minister | Date appointed | |
|---|---|---|---|
| PS to the Minister of Home Affairs | Benjamin Disraeli Goldberg | 23 November 1956 – 11 December 1958 | |
| John Foot | 11 December 1958 – 31 December 1963 | ||
| PS to the Minister of Home Affairs (Race Relations) | Jasper Zengeza Savanhu | 3 April 1959 – 14 August 1962 | |
| PS to the Minister of Transport and Works | George Wellington Rex L'Ange | 23 November 1956 – 11 December 1958 | |
| PS to the Minister of External Affairs | Godwin Akabiwa Mbikusita Lewanika | 7 May 1962 – 31 December 1963 | |
| PS to the Minister of Defence, Economic Affairs and Power | Sydney Stanford Sawyer | 7 May 1962 – 31 December 1963 |