| Cabinet Name: | Second Hassan Rouhani Cabinet |
| Cabinet Number: | 12th |
| Jurisdiction: | Islamic Republic of Iran |
| Flag: | Flag of Iran.svg |
| Flag Border: | true |
| Incumbent: | President of Iran |
| Date Formed: | 3 August 2017 |
| Date Dissolved: | 3 August 2021 |
| Government Head: | Hassan Rouhani |
| Deputy Government Head: | Eshaq Jahangiri |
| State Head: | Ali Khamenei |
| Current Number: | 19 |
| Former Members Number: | 6 |
| Total Number: | 25 |
| Election: | 2017 Iranian presidential election |
| Legislature Term: | 10th term |
| Incoming Formation: | Confirmation of Hassan Rouhani's cabinet (2017) |
| Previous: | Rouhani I |
| Successor: | Raisi |
Hassan Rouhani was the seventh President of Iran which governs during his second term within the twelfth government of the Islamic Republic of Iran.
See also: Confirmations of Hassan Rouhani's Cabinet.
|-|-!colspan=7|* Acting|-
Despite the pressure coming from his supporters and women's rights activists to appoint female ministers, Rouhani did not name any woman as minister, however he appointed three women in his second administration, Masoumeh Ebtekar and Laya Joneydi as vice presidents and Shahindokht Molaverdi as his aide for citizenship rights.