| Type: | Bishop |
| Honorific-Prefix: | Most Reverend |
| Gonzalo Hernandez y Hermosillo y Gonzalez | |
| Bishop of Durango | |
| Church: | Catholic Church |
| Diocese: | Diocese of Durango |
| Term: | 1620–1631 |
| Predecessor: | None |
| Successor: | Alfonso de Franco y Luna |
| Consecration: | 30 November 1621 |
| Consecrated By: | Juan Pérez de la Serna |
| Birth Date: | 1560 |
| Birth Place: | México |
| Death Date: | 28 January 1631 |
| Death Place: | Durango, México |
| Nationality: | Mexican |
Gonzalo Hernandez y Hermosillo y Gonzalez, O.S.A. (1560 – 28 January, 1631) was a Roman Catholic prelate who served as the first Bishop of Durango (1620–1631).
Gonzalo Hernandez y Hermosillo y Gonzalez was born in México in 1560 and ordained a priest in the Order of Saint Augustine.[1] On 12 October 1620, he was appointed during the papacy of Pope Paul V as Bishop of Durango. On 30 November 1621, he was consecrated bishop by Juan Pérez de la Serna, Archbishop of México. He served as Bishop of Durango until his death on 28 January 1631.