| Gmina Brzeźnio | |
| Other Name: | Brzeźnio Commune |
| Settlement Type: | Gmina |
| Total Type: | Total |
| Subdivision Type: | Country |
| Subdivision Type1: | Voivodeship |
| Subdivision Name1: | Łódź |
| Subdivision Type2: | County |
| Subdivision Name2: | Sieradz |
| Area Total Km2: | 128.73 |
| Population Total: | 6351 |
| Population As Of: | 2006 |
| Population Density Km2: | auto |
| Coor Pinpoint: | Brzeźnio |
| Coordinates: | 51.4947°N 18.6219°W |
| Seat: | Brzeźnio |
| Blank Name: | Car plates |
| Blank Info: | ESI |
Gmina Brzeźnio is a rural gmina (administrative district) in Sieradz County, Łódź Voivodeship, in central Poland. Its seat is the village of Brzeźnio, which lies approximately 15km (09miles) south-west of Sieradz and 670NaN0 south-west of the regional capital Łódź.
The gmina covers an area of 128.73km2, and as of 2006 its total population is 6,351.
Gmina Brzeźnio contains the villages and settlements of Barczew, Borowiska, Bronisławów, Brzeźnio, Dębołęka, Gęsina, Gozdy, Kliczków Mały, Kliczków Wielki, Kliczków-Kolonia, Krzaki, Lipno, Nowa Wieś, Ostrów, Podcabaje, Próba, Pustelnik, Pyszków, Rembów, Ruszków, Rybnik, Rydzew, Stefanów Barczewski Drugi, Stefanów Barczewski Pierwszy, Stefanów Ruszkowski, Wierzbowa, Wola Brzeźniowska, Zapole and Złotowizna.
Gmina Brzeźnio is bordered by the gminas of Brąszewice, Burzenin, Sieradz, Wróblew and Złoczew.