Glycoside hydrolase family 101 explained

Symbol:	Glyco_hydro_101
Endo-alpha-N-acetylgalactosaminidase
Pfam:	PF12905
Pfam Clan:	CL0058
Cazy:	GH101
Cdd:	cd14244

Symbol:	GHL
Glycoside hydrolases related to GH101 family
Pfam:	PF11308
Pfam Clan:	CL0058

In molecular biology, glycoside hydrolase family 101 is a family of glycoside hydrolases.

Glycoside hydrolases are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycoside hydrolases, based on sequence similarity, has led to the definition of >100 different families.^{[1] [2] [3]} This classification is available on the CAZy web site,^{[4] [5]} and also discussed at CAZypedia, an online encyclopedia of carbohydrate active enzymes.^{[6] [7]}

Glycoside hydrolase family GH101 includes enzymes with endo-α-N-acetylgalactosaminidase activity and can be split into several subfamilies.^[8]

External links

• GH101 in CAZypedia

Notes and References

1. Henrissat B, Callebaut I, Mornon JP, Fabrega S, Lehn P, Davies G . Conserved catalytic machinery and the prediction of a common fold for several families of glycosyl hydrolases . Proc. Natl. Acad. Sci. U.S.A. . 92 . 15 . 7090–7094 . 1995 . 7624375 . 10.1073/pnas.92.15.7090 . 41477. 1995PNAS...92.7090H . free .
2. Henrissat B, Davies G . Structures and mechanisms of glycosyl hydrolases . Structure . 3 . 9 . 853–859 . 1995 . 8535779 . 10.1016/S0969-2126(01)00220-9. free .
3. Web site: Bairoch, A. "Classification of glycosyl hydrolase families and index of glycosyl hydrolase entries in SWISS-PROT". 1999. . 2011-10-05 . 2011-05-25 . https://web.archive.org/web/20110525140109/http://www.expasy.ch/cgi-bin/lists?glycosid.txt . dead .
4. Web site: Home. CAZy.org. en. 2018-03-06.
5. Lombard. Vincent. Golaconda Ramulu. Hemalatha. Drula. Elodie. Coutinho. Pedro M.. Henrissat. Bernard. 2014-01-01. The carbohydrate-active enzymes database (CAZy) in 2013. Nucleic Acids Research. en. 42. D1. D490–D495. 10.1093/nar/gkt1178. 24270786. 3965031. 0305-1048.
6. Web site: Glycoside Hydrolase Family 101. CAZypedia.org. en. 2018-03-06.
7. CAZypedia Consortium. 2018-12-01. Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes. Glycobiology. 28. 1. 3–8. 10.1093/glycob/cwx089. 1460-2423. 29040563. 21.11116/0000-0003-B7EB-6. free.
8. Naumoff DG. GH101 family of glycoside hydrolases: subfamily structure and evolutionary connections with other families. . J Bioinform Comput Biol . 2010 . 8 . 3 . 437–451 . 20556855 . 10.1142/s0219720010004628.