Glycine receptor antagonist explained

A glycine receptor antagonist is a drug which acts as an antagonist of the glycine receptor.^{[1] [2]}

Examples

Antagonists

• Selective
  • Brucine
  • Strychnine
  • Tutin
• Non-selective
  • Bicuculline
  • Caffeine
  • Picrotoxin
  • Pitrazepin
  • Thiocolchicoside

See also

• Glycine receptor agonist

Notes and References

1. Miyakawa. N. Uchino. S. Yamashita. T. Okada. H. Nakamura. T. Kaminogawa. S. Miyamoto. Y. Hisatsune. T. A glycine receptor antagonist, strychnine, blocked NMDA receptor activation in the neonatal mouse neocortex.. NeuroReport. 16 September 2002. 13. 13. 1667–73. 12352624. 10.1097/00001756-200209160-00020. 34027498.
2. Vandenberg. RJ. Handford. CA. Schofield. PR. Distinct agonist- and antagonist-binding sites on the glycine receptor.. Neuron. September 1992. 9. 3. 491–6. 1326295. 10.1016/0896-6273(92)90186-h. 45100334 .