Glycine oxidase explained

Glycine oxidase
Ec Number:	1.4.3.19
Cas Number:	39307-16-9
Width:	270

Glycine oxidase is an enzyme with systematic name glycine:oxygen oxidoreductase (deaminating).^{[1] [2]} This enzyme catalyses the following chemical reaction

glycine + H₂O + O₂

\rightleftharpoons glyoxylate + NH₃ + H₂O₂ (overall reaction)

(1a) glycine + O₂

\rightleftharpoons 2-iminoacetate + H₂O₂

(1b) 2-iminoacetate + H₂O

\rightleftharpoons glyoxylate + NH₃

This flavoenzyme containing non-covalently bound FAD.

Notes and References

1. Job V, Marcone GL, Pilone MS, Pollegioni L . Glycine oxidase from Bacillus subtilis. Characterization of a new flavoprotein . The Journal of Biological Chemistry . 277 . 9 . 6985–93 . March 2002 . 11744710 . 10.1074/jbc.M111095200 . free .
2. Nishiya Y, Imanaka T . Purification and characterization of a novel glycine oxidase from Bacillus subtilis . FEBS Letters . 438 . 3 . 263–6 . November 1998 . 9827558 . 10.1016/s0014-5793(98)01313-1 . free .