Glucose 1-dehydrogenase explained

glucose 1-dehydrogenase
Ec Number:1.1.1.47
Cas Number:9028-53-9
Go Code:0047936
Width:270

In enzymology, a glucose 1-dehydrogenase is an enzyme that catalyzes the chemical reaction

beta-D-glucose + NAD(P)+

\rightleftharpoons

D-glucono-1,5-lactone + NAD(P)H + H+

The 3 substrates of this enzyme are beta-D-glucose, NAD+, and NADP+, whereas its 4 products are D-glucono-1,5-lactone, NADH, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is beta-D-glucose:NAD(P)+ 1-oxidoreductase. Another name in common use is D-glucose dehydrogenase (NAD(P)+).

Structural studies

As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes,,,,,,,, and .

References

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Glucose 1-dehydrogenase".

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