Glucan 1,6-α-glucosidase explained

Glucan 1,6-α-glucosidase
Ec Number:	3.2.1.70
Cas Number:	37288-48-5

Glucan 1,6-α-glucosidase (exo-1,6-β-glucosidase, glucodextrinase, glucan α-1,6-D-glucohydrolase) is an enzyme with systematic name glucan 6-α-D-glucohydrolase.^{[1] [2] [3]} It catalyses the hydrolysis of (1→6)-α-D-glucosidic linkages in (1→6)-α-D-glucans and derived oligosaccharides

Hydrolysis is accompanied by inversion at C-1, so that new reducing ends are released in the β-configuration.

Notes and References

1. Some catalytic properties of an exo-1,6-α-glucosidase (glucodextranase) from Arthrobacter globiformis I42 . Ohya T, Sawai T, Uemura S, Abe K . Agric. Biol. Chem. . 1978 . 42 . 3 . 571–577 . 10.1271/bbb1961.42.571. free .
2. Preparation and some properties of Arthrobacter globiformis exo-1,6-α-glucosidase . Sawai T, Yamaki T, Ohya T . Agric. Biol. Chem. . 1976 . 40 . 1293–1299 . 10.1271/bbb1961.40.1293. free .
3. Walker GJ, Pulkownik A . Degradation of dextrans by an α-1,6-glucan glucohydrolase from Streptococcus mitis . Carbohydrate Research . 29 . 1 . 1–14 . July 1973 . 4356399 . 10.1016/s0008-6215(00)82066-2 .