Glicaramide Explained

Glicaramide (SQ-65993) is an orally bioavailable anti-diabetic medication.[1] It has a similar potency as glibenclamide (glyburide) in the class of medication known as sulfonylureas. Its structure is similar since it has a cyclic acyl group which replaces the latter's 2-methoxy-5-chlorobenzyl.[2] Same as glibenclamide, it is classified as a second-generation sulfonylurea. It may have more pronounced extra-pancreatic effects than glibenclamide or tolbutamide.

See also

Notes and References

  1. Höhn H, Polacek I, Schulze E . Potential antidiabetic agents. Pyrazolo(3,4-b)pyridines . Journal of Medicinal Chemistry . 16 . 12 . 1340–6 . December 1973 . 4358224 . 10.1021/jm00270a006 .
  2. Book: 1981 . Sarges R . Hypoglycemic Drugs . Ellis GP, West GB . Progress in Medicinal Chemistry . 1981 . 18 . https://books.google.com/books?id=FC9pDtB_tz0C&pg=PA202 . 202 . Elsevier Science . 0-444-80345-9 . 2016-10-18 . 2023-01-28 . https://web.archive.org/web/20230128020246/https://books.google.com/books?id=FC9pDtB_tz0C&pg=PA202 . live .

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Glicaramide".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.