| Type: | Cardinal |
| Honorific Prefix: | His Eminence |
| Giuseppe D'Annibale | |
| Prefect of the Congregation for Indulgences and Sacred Relics | |
| Church: | Roman Catholic Church |
| Appointed: | 22 June 1890 |
| Term End: | 18 July 1892 |
| Predecessor: | Carlo Cristofori |
| Successor: | Luigi Sepiacci |
| Other Post: | Cardinal-Priest of Santi Bonifacio ed Alessio (1889-92) |
| Ordination: | 21 September 1839 |
| Ordained By: | Filippo de’ Conti Curoli |
| Consecration: | 14 August 1881 |
| Consecrated By: | Raffaele Monaco La Valletta |
| Cardinal: | 11 February 1889 |
| Created Cardinal By: | Pope Leo XIII |
| Rank: | Cardinal-Priest |
| Birth Name: | Giuseppe D'Annibale |
| Birth Date: | 22 September 1815 |
| Birth Place: | Borbona, Rieti, Papal States |
| Death Place: | Borbona, Rieti, Kingdom of Italy |
| Parents: | Giuseppe D'Annibale Maddalena Marinucci |
| Previous Post: | Titular Bishop of Carystus (1881-89) |
Giuseppe d'Annibale (22 September 1815 – 18 July 1892) was an Italian Catholic cardinal and theologian.
He was appointed professor in the Seminary of Rieti and later vicar-general of the diocese. He was preconized Titular Bishop of Caryste by Pope Leo XIII on 12 August 1881, was created Cardinal-Priest of Santi Bonifacio e Alessio on 11 February 1889, and became Prefect of the Congregation for Indulgences and Sacred Relics.
Among d'Annibale's works is a treatise on moral theology, entitled "Summula theologiae moralis" (Milan, 1881–1883). He also wrote a commentary on the Constitution "Apostolicae Sedis" (Rieti, 1880).