| Giro del Mendrisiotto | |
| Date: | Mid-March |
| Region: | Ticino, Switzerland |
| English: | Tour of Mendrisiotto |
| Discipline: | Road |
| Competition: | UCI Europe Tour |
| Type: | Single day race |
| Number: | 72 (as of 2012) |
| Mostwins: | (3 wins) |
Giro del Mendrisiotto is a road bicycle race held annually around Mendrisio, in the canton of Ticino of Switzerland. The race was an amateur competition until 1996. Since 2005, it is organized as a 1.2 event on the UCI Europe Tour.In 2010 the race was excluded from the UCI calendar, once again becoming a national event.