| Giorgio Sereni | |
| Height: | 1.79 m |
| Birth Date: | 1935 9, df=yes |
| Birth Place: | Brescia, Italy |
| Position: | defender |
| Years1: | 1955–1957 |
| Clubs1: | Reggiana |
| Years2: | 1957–1963 |
| Clubs2: | Palermo |
| Years3: | 1963–1969 |
| Clubs3: | Padova |
| Manageryears1: | 1969–1970 |
| Managerclubs1: | Venezia |
| Manageryears2: | 1970–1971 |
| Managerclubs2: | Reggiana (assistant) |
| Manageryears3: | 1972–1973 |
| Managerclubs3: | Parma |
| Manageryears4: | 1977–1978 |
| Managerclubs4: | Catanzaro |
| Manageryears5: | 1978–1979 |
| Managerclubs5: | Rimini |
| Manageryears6: | 1979–1980 |
| Managerclubs6: | Foggia |
| Manageryears7: | 1980–1981 |
| Managerclubs7: | Parma |
| Manageryears8: | 1981–1982 |
| Managerclubs8: | Rende |
| Manageryears9: | 1982–1983 |
| Managerclubs9: | SSC Campania |
| Manageryears10: | 1983–1984 |
| Managerclubs10: | Padova |
| Manageryears11: | 1984–1985 |
| Managerclubs11: | SSC Campania |
| Manageryears12: | 1985–1986 |
| Managerclubs12: | Salernitana |
| Manageryears13: | 1986–1987 |
| Managerclubs13: | Siena |
| Manageryears14: | 1988–1989 |
| Managerclubs14: | Monopoli |
| Manageryears15: | 1991–1992 |
| Managerclubs15: | Giulianova |
Giorgio Sereni (3 September 1935 — 6 October 2010) was an Italian football defender and later manager.