Gingipain K Explained

Gingipain K
Ec Number:3.4.22.47
Cas Number:159745-69-4

Gingipain K (Lys-gingipain, PrtP proteinase) is an enzyme.[1] [2] This enzyme catalyses the following chemical reaction:

Endopeptidase with strict specificity for lysyl bonds

Activity of this enzyme is stimulated by glycine.

See also

Notes and References

  1. Pike R, McGraw W, Potempa J, Travis J . Lysine- and arginine-specific proteinases from Porphyromonas gingivalis. Isolation, characterization, and evidence for the existence of complexes with hemagglutinins . The Journal of Biological Chemistry . 269 . 1 . 406–11 . January 1994 . 8276827 .
  2. Curtis MA, Aduse Opoku J, Rangarajan M, Gallagher A, Sterne JA, Reid CR, Evans HE, Samuelsson B . Attenuation of the virulence of Porphyromonas gingivalis by using a specific synthetic Kgp protease inhibitor . Infection and Immunity . 70 . 12 . 6968–75 . December 2002 . 12438376 . 132948 . 10.1128/iai.70.12.6968-6975.2002 .