Gilvocarcin V Explained

Gilvocarcin V is an antitumor agent and an antibiotic which is active against Gram-positive bacteria with the molecular formula C₂₇H₂₆O₉. Gilvocarcin V is produced by the bacterium Streptomyces griseoflavus and other Streptomyces bacteria.^{[1] [2] [3] [4]} Gilvocarcin V is a strong inhibitor of the DNA synthesis.^[4]

Further reading

• Book: Gillum . Karen D. . Lethal and Mutagenic Effects of Antitumor Agent Gilvocarcin V Photosensitization on Escherichia Coli K-12/343/120 . 1988 . Texas Southern University . en.
• Book: Publishers . Bentham Science . Current Organic Chemistry . November 1997 . Bentham Science Publishers . 408 . en.
• Book: Transferases—Advances in Research and Application: 2012 Edition . 26 December 2012 . ScholarlyEditions . 978-1-4649-9789-1 . 137 . en.
• Book: Diana . Patrizia . Cirrincione . Girolamo . Biosynthesis of Heterocycles: From Isolation to Gene Cluster . 9 February 2015 . John Wiley & Sons . 978-1-118-02867-4 . 585 . en.

Notes and References

1. Book: Comprehensive Natural Products II: Chemistry and Biology . 5 March 2010 . Elsevier . 978-0-08-045382-8 . 257 . en.
2. Book: Buckingham . John . Dictionary of Organic Compounds . 1987 . Taylor & Francis . 978-0-412-17050-8 . 359 . en.
3. Fischer . Carsten . Lipata . Fredilyn . Rohr . Jürgen . The Complete Gene Cluster of the Antitumor Agent Gilvocarcin V and Its Implication for the Biosynthesis of the Gilvocarcins . Journal of the American Chemical Society . 1 July 2003 . 125 . 26 . 7818–7819 . 10.1021/ja034781q. 12822997 . 4480634 .
4. Book: Progress in Medicinal Chemistry . 1 January 1985 . Elsevier . 978-0-08-086270-5 . 20 . en.