| Gilles Ruyssen | |
| Birth Date: | 18 June 1994 |
| Birth Place: | Belgium |
| Height: | 1.86m (06.1feet) |
| Position: | Center back |
| Currentclub: | Dender |
| Clubnumber: | 16 |
| Youthyears1: | 1999–2006 |
| Youthclubs1: | Ronse |
| Youthyears2: | 2006–2014 |
| Youthclubs2: | Gent |
| Years1: | 2013–2014 |
| Caps1: | 1 |
| Goals1: | 0 |
| Years2: | 2014–2017 |
| Caps2: | 32 |
| Goals2: | 1 |
| Years3: | 2017–2018 |
| Caps3: | 32 |
| Goals3: | 4 |
| Years4: | 2018–2023 |
| Clubs4: | RWDM47 |
| Caps4: | 105 |
| Goals4: | 9 |
| Years5: | 2023– |
| Caps5: | 35 |
| Goals5: | 2 |
| Nationalyears1: | 2013 |
| Nationalteam1: | Belgium U19 |
| Nationalcaps1: | 4 |
| Nationalgoals1: | 0 |
| Club-Update: | 12 May 2024 |
Gilles Ruyssen (born 18 June 1994) is a Belgian professional footballer who plays for Dender in the Challenger Pro League as a center back.
He made his Belgian Pro League debut on 3 May 2014 in the last game of the 2013–14 season for Gent against K. Lierse S.K. He played the full game in a 4-0 home win at the Ghelamco Arena.[1]