| Gilles Eyquem | |
| Fullname: | Gilles Eyquem |
| Birth Date: | 30 May 1959 |
| Birth Place: | Bordeaux, France |
| Position: | Defender |
| Years1: | 1977–1982 |
| Years2: | 1982–1983 |
| Years3: | 1983–1985 |
| Years4: | 1985–1987 |
| Years5: | 1987–1989 |
| Years6: | 1989–1991 |
| Clubs6: | Cherbourg |
| Caps1: | 46 |
| Caps2: | 0 |
| Caps3: | 46 |
| Caps4: | 67 |
| Caps5: | 61 |
| Caps6: | ? |
| Goals1: | 0 |
| Goals2: | 0 |
| Goals3: | 1 |
| Goals4: | 1 |
| Goals5: | 3 |
| Goals6: | ? |
| Manageryears1: | 1989–1991 |
| Managerclubs3: | France U16 |
Gilles Eyquem (in French pronounced as /ʒil ekɛm/; born 30 May 1959 in Bordeaux, France) is a former professional footballer. He played as a central defender and is currently manager of the France under-16 national team.