| Gifford Creek | |
| Pushpin Map: | New York |
| Pushpin Map Caption: | Location of the mouth of Gifford Creek |
| Subdivision Type1: | Country |
| Subdivision Name1: | United States |
| Subdivision Type2: | State |
| Subdivision Name2: | New York |
| Subdivision Type4: | County |
| Subdivision Name4: | Otsego |
| Source1 Coordinates: | 42.5142°N -75.0279°W |
| Mouth: | Susquehanna River |
| Mouth Coordinates: | 42.459°N -75.0063°W[1] |
| Mouth Elevation: | 1083feet |
Gifford Creek is a river in Otsego County, New York. It converges with the Susquehanna River east of Oneonta.