Giant solitary trichoepithelioma explained

Giant solitary trichoepithelioma is a cutaneous condition characterized by a skin lesion that may be up to several centimetres in diameter.^[1]

Signs and symptoms

Giant solitary trichoepithelioma primarily affects the perianal and groin region.^[2] They typically measure a few centimeters in diameter and rarely reach 2 to 3 cm.^[3]

Diagnosis

Giant solitary trichoepithelioma is distinguished histologically by a dermal or subcutaneous tumor made up of basophilic cells grouped in solid, adenoid, or lace-like clusters. The cells have a sparse cytoplasm and a darkly pigmented nucleus, and the tumor islands exhibit the typical peripheral cell palisading. Papillary bodies and trichilemmal keratinization in horn cysts are indicative of a solid diagnosis, however they are not always present. Failures to develop papillary mesenchyme are represented by papillary bodies.^[4]

Treatment

The preferred course of treatment is either radiosurgical ablation or surgical excision, with or without a flap.^[4]

See also

• Trichoepithelioma
• Skin lesion

Further reading

• Martinez . Carlos Augusto Real . Priolli . Denise Gonçalves . Piovesan . Helenice . Waisberg . Jaques . Nonsolitary Giant Perianal Trichoepithelioma With Malignant Transformation Into Basal Cell Carcinoma: Report of a Case and Review of the Literature . Diseases of the Colon & Rectum . Ovid Technologies (Wolters Kluwer Health) . 47 . 5 . 2004 . 0012-3706 . 10.1007/s10350-003-0104-8 . 773–777 . 15073659 . none.
• Bubna . AdityaKumar . Patil . NitinKrishna . Hussain . Seeba . Singh . Neha . Giant solitary trichoepithelioma: A diagnosis of exclusion . International Journal of Trichology . Medknow . 14 . 6 . 2022 . 221–223 . 0974-7753 . 10.4103/ijt.ijt_9_21 . free . 37034549 . none. 10075344 .

Notes and References

1. Book: James, William D. . Berger, Timothy G. . Andrews' Diseases of the Skin: Clinical Dermatology . Saunders Elsevier . 2006 . 0-7216-2921-0 . etal.
2. Teli . Bhavuray . Thrishuli . P. B. . Santhosh . R. . Amar . D. N. . Rajpurohit . Shravan . Giant solitary trichoepithelioma . South Asian Journal of Cancer . Georg Thieme Verlag KG . 04 . 1 . 2015 . 2278-330X . 10.4103/2278-330x.149951 . free . 041–044. 25839021 . 4382785 .
3. Genc . Selahattin . Sirin Ugur . Seher . Arslan . Ilker Burak . Demir . Ahmet . Tuhanioglu . Birgul . Kuskonmaz . Ibrahim . Eruyar . Tugrul . Selcuk . Adin . A Giant Solitary Trichoepithelioma Originating from the Auricle . Dermatologic Surgery . 38 . 9 . 2012 . 1076-0512 . 10.1111/j.1524-4725.2012.02483.x . 1527–1528. 22691160 .
4. Swaroop . MukundaRanga . Sathyanarayana . BelagolaDassegowda . Chaurasia . PriyankaKumari . Devaraj . Yogesh . Dukkipati . Monica . Sajid . Aneesa . Giant solitary trichoepithelioma over the nose . Indian Journal of Dermatopathology and Diagnostic Dermatology . 4 . 1 . 2017 . 2349-6029 . 10.4103/ijdpdd.ijdpdd_65_16 . free . 17.