| Honorific-Prefix: | Most Reverend |
| Giacomo di Santa Lucia | |
| Archbishop (personal title) of Patti | |
| Church: | Catholic Church |
| Diocese: | Diocese of Patti |
| Term: | 1480–1482 |
| Successor: | Giacomo Antonio Leofanti |
| Death Date: | 1482 |
| Death Place: | Patti, Italy |
| Previous Post: | Archbishop of Messina (1474–1480) |
Giacomo di Santa Lucia (died 1482) was a Roman Catholic prelate who served as Archbishop (personal title) of Patti (1480–1482) and Archbishop of Messina (1474–1480).[1]
Giacomo di Santa Lucia was ordained a priest in the Order of Friars Minor. On 23 May 1474, he was appointed by Pope Sixtus IV as Archbishop of Messina. On 7 July 1480, he was appointed by Pope Sixtus IV as Archbishop (personal title) of Patti and Titular Archbishop of Philippi. He served as Archbishop of Patti until his death in 1482.