| Giacomo Natoli | |
| Birth Date: | 27 August 1846 |
| Death Place: | Messina, Sicily |
| Parents: | Giuseppe Natoli, Maria Cardile |
| Honors: | knight, Order of the Crown of Italy |
Giacomo Natoli (born 27 August 1846) was an Italian cavalry officer. He was three times sindaco or mayor of Messina, in the Mediterranean island of Sicily. On 11 March 1889 he obtained ministerial recognition of the title of nobility 'Barone di Scaliti'.