Ghukasyan (Armenian: Ղուկասյան) in Armenian pronounced as /ʁɔvkɑˈsjɑn/ pronounced as /ru/) is an Armenian surname, meaning 'son of Ghukas', the Armenian equivalent of Luke. In Russia, Azerbaijan and other countries, some holders of this surname changed the spelling to Gukasov (Russian: Гука́сов|ɡʊˈkasəf).
People with the surname include: