Ghodsi (Persian: قدسی, literally "sacred", "sacramental"; transcription from the Persian script of the adjective form of Ghods/Quds (Arabic: [[:wikt:القدس|القدس]]), the corresponding transliteration from the Arabic script being Qudsi (lit.: Jerusalemite, someone whose family originated from Jerusalem) is a Persian surname.
Notable people with the surname include: