Germinal epithelium (female) explained

Germinal epithelium (female)

The ovarian surface epithelium, also called the germinal epithelium of Waldeyer,[1] or coelomic epithelium, is a layer of simple squamous-to-cuboidal epithelial cells covering the ovary.[2]

The term germinal epithelium is a misnomer as it does not give rise to primary follicles.[3]

Composition

These cells are derived from the mesoderm during embryonic development and are closely related to the mesothelium of the peritoneum. The germinal epithelium gives the ovary a dull gray color as compared with the shining smoothness of the peritoneum; and the transition between the mesothelium of the peritoneum and the cuboidal cells which cover the ovary is usually marked by a line around the anterior border of the ovary.

Diseases

Ovarian surface epithelium can give rise to surface epithelial-stromal tumor.

Notes and References

  1. Nishida T, Nishida N . Reinstatement of "germinal epithelium" of the ovary . Reprod Biol Endocrinol . 4 . 42 . 2006 . 16923182 . 1560142 . 10.1186/1477-7827-4-42 . free .
  2. Auersperg . N. . Wong . A. S. . Choi . K. C. . Kang . S. K. . Leung . P. C. . Ovarian Surface Epithelium: Biology, Endocrinology, and Pathology . Endocrine Reviews . 22 . 2 . 255–288 . 2001 . 10.1210/edrv.22.2.0422 . 11294827. 11013148 . free .
  3. Book: Histology: A Text and Atlas . Lippincott Williams & Wilkins . Ross M, Pawlina W . 2011 . 978-0-7817-7200-6 . 832 . 6th.