| State: | GA |
| Type: | SR |
| Route: | 65 |
| Maint: | Georgia Department of Transportation |
| Map Custom: | yes |
| Map Notes: | SR 65 highlighted in red |
| Length Mi: | 17.0 |
| Length Round: | 1 |
| Direction A: | West |
| Terminus A: | west of Hopeful |
| Junction: | south-southwest of Camilla |
| Direction B: | East |
| Terminus B: | in Pelham |
| Counties: | Mitchell |
| Previous Type: | SR |
| Previous Route: | 64 |
| Next Type: | SR |
| Next Route: | 66 |
State Route 65 (SR 65) is a 17adj=midNaNadj=mid state highway located entirely in the southwestern part of Mitchell County in the southwestern part of the U.S. state of Georgia. It connects the Hopeful and Pelham areas of the state.
SR 65 begins at an intersection with SR 311, west of Hopeful. It heads southeast and curves to the east toward Pelham. The route has an intersection with SR 97 in Hopeful. The highway travels east-southeast through rural portions of the county and passes through the town of Branchville. It has an intersection with SR 112 before reaching Pelham. Once in Pelham, the route gradually bends to the east-southeast, until it meets its eastern terminus, an intersection with SR 93.