| Genre: | Sitcom |
| Creator: | Rob Long Dan Staley |
| Director: | James Burrows Pamela Fryman Michael Lessac Philip Charles MacKenzie Brian K. Roberts |
| Starring: | Bob Newhart Judd Hirsch Jason Bateman Bess Meyer Robyn Lively |
| Composer: | Christophe Beck |
| Country: | United States |
| Language: | English |
| Num Seasons: | 1 |
| Num Episodes: | 22 |
| Executive Producer: | Rob Long Dan Staley |
| Producer: | Tim Berry Stephen C. Grossman |
| Runtime: | 22 minutes |
| Company: | Staley-Long Productions Paramount Television |
| Channel: | CBS |
George and Leo is an American sitcom television series starring Bob Newhart and Judd Hirsch that aired on CBS from September 15, 1997 to March 16, 1998.
Newhart and Hirsch starred as the respective title characters, widely divergent men who become in-laws when their children get married. George's (Newhart) son was played by Jason Bateman. Bess Meyer initially played Leo's (Hirsch) daughter, but was replaced after the first eight episodes by Robyn Lively. The series was set on Martha's Vineyard, where George owned a bookstore.
One episode, "The Cameo Show", featured guest appearances from many of the costars of Newhart's and Hirsch's previous sitcoms: The Bob Newhart Show, Taxi, Newhart, and Dear John. The series was cancelled after 22 episodes due to low ratings.