| George Smith | |
| Position: | Pitcher |
| Bats: | Right |
| Throws: | Right |
| Birth Date: | October 27, 1901 |
| Birth Place: | Louisville, Kentucky |
| Death Place: | Richmond, Virginia |
| Debutleague: | MLB |
| Debutdate: | April 21 |
| Debutteam: | Detroit Tigers |
| Finalleague: | MLB |
| Finaldate: | September 17 |
| Finalteam: | Boston Red Sox |
| Statleague: | MLB |
| Stat1label: | Win–loss record |
| Stat1value: | 10–8 |
| Stat2label: | Strikeouts |
| Stat2value: | 135 |
| Stat3label: | ERA |
| Stat3value: | 5.28 |
| Teams: |
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George Shelby Smith (October 27, 1901 – May 26, 1981) was a middle relief pitcher in Major League Baseball who played from through for the Detroit Tigers (1926–1929) and Boston Red Sox (1930). Listed at, 175 lb., Smith batted and threw right-handed. He was born in Louisville, Kentucky. In a four-season career, Smith posted 10–8 record with a 5.28 ERA in 132 appearances, including seven starts, one complete game, saves, 135 strikeouts, and innings of work.
He gave up one of Babe Ruth's record-setting 60 home runs during the 1927 New York Yankees season.
Smith died at the age of 79 in Richmond, Virginia.