| George Seabrook Bryan | |
| Office: | Judge of the United States District Court for the District of South Carolina |
| Term Start: | March 12, 1866 |
| Term End: | September 1, 1886 |
| Appointer: | Andrew Johnson |
| Predecessor: | Andrew Gordon Magrath |
| Successor: | Charles Henry Simonton |
| Birth Name: | George Seabrook Bryan |
| Birth Date: | 22 May 1809 |
| Birth Place: | Charleston, South Carolina |
| Death Place: | Flat Rock, North Carolina |
| Education: | read law |
George Seabrook Bryan (May 22, 1809 – September 28, 1905) was a United States district judge of the United States District Court for the District of South Carolina.
Born in Charleston, South Carolina, Bryan read law to enter the bar.
On February 9, 1866, Bryan was nominated by President Andrew Johnson to a seat on the United States District Court for the District of South Carolina vacated by Judge Andrew Gordon Magrath. Bryan was confirmed by the United States Senate on March 12, 1866, and received his commission the same day. Bryan's service was terminated on September 1, 1886, due to his retirement.
Bryan died on September 28, 1905, in Flat Rock, Henderson County, North Carolina.