George Smith (chemist) explained

George Smith
Birth Name:George Pearson Smith[1]
Birth Date:1941 3, df=yes
Birth Place:Norwalk, Connecticut, U.S.
Known For:Phage display
Thesis Title:The variation and adaptive expression of antibodies.
Thesis Url:https://books.google.com/books?id=vmKV0hs-mdAC
Thesis Year:1970
Spouse:Marjorie Sable[2]
Doctoral Advisor:Edgar Haber
Awards:2018 Nobel Prize in Chemistry

George Pearson Smith (born 10 March 1941)[3] [4] is an American biologist and Nobel laureate.[5] He is a Curators' Distinguished Professor Emeritus of Biological Sciences at the University of Missouri in Columbia, Missouri, US.

Career

Born in Norwalk, Connecticut, he earned his A.B. degree from Haverford College in biology, was a high school teacher and lab technician for a year, and earned his PhD degree in bacteriology and immunology from Harvard University.[6] He was a postdoc at the University of Wisconsin (with future Nobel laureate Oliver Smithies) before moving to Columbia, Missouri and joining the University of Missouri faculty in 1975. He spent the 1983–1984 academic year at Duke University with Robert Webster where he began the work that led to him being awarded a Nobel Prize.[7] [8] [9] [10]

He is best known for phage display, a technique where a specific protein sequence is artificially inserted into the coat protein gene of a bacteriophage, causing the protein to be expressed on the outside of the bacteriophage. Smith first described the technique in 1985 when he displayed peptides on filamentous phage by fusing the peptide of interest onto gene III of filamentous phage.[8] He was awarded the 2018 Nobel Prize in Chemistry for this work, sharing his prize with Greg Winter and Frances Arnold.

Human rights advocacy

Smith is an advocate for equal rights for Palestinians and Israeli Jews in their common homeland, and a strong supporter of the Boycott, Divestment and Sanctions movement.[11] On the topic of religion, Smith is quoted as saying "I'm not religious or Jewish by birth. But my wife is Jewish and our sons are bar-mitzvahed, and I'm very engaged with Jewish culture and politics."[12]

Awards and honors

External links

Notes and References

  1. News: Novelty Reigns at Bridal in Maryland . The New York Times. 7 October 2018. 11 June 1970 .
  2. Web site: Williams . Mará Rose . 'My first standing ovation': Humble MU professor cheered after winning Nobel Prize . Kansas City Star . 7 October 2018.
  3. Web site: 6 October 2018 . George P. Smith – Facts – 2018 . NobelPrize.org . Nobel Media AB . 6 October 2018.
  4. Web site: Nobel Prize in Chemistry Honors Work That Demonstrates 'The Power of Evolution'. . 3 October 2018 . Sullivan . Emily . Greenfieldboyce . Nell .
  5. News: Nobel Prize in Chemistry 2018 – live . 3 October 2018. The Guardian . 3 October 2018 .
  6. The variation and adaptive expression of antibodies . 1971 . . PhD . Smith . George Pearson . . subscription . 76998014. 1445740 .
  7. Web site: Tropical and Molecular Parasitology Seminar Series. 3 October 2018.
  8. Smith GP . Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface . Science . 228 . 4705 . 1315–7 . June 1985 . 4001944 . 10.1126/science.4001944 . 1985Sci...228.1315S .
  9. Web site: 2018 Nobel Prize winner did much of his work at Duke University. 3 October 2018. 3 October 2018.
  10. Book: Phage Display of Peptides and Proteins: A Laboratory Manual. 1996. Academic Press, Inc.. 978-0-12-402380-2. en.
  11. News: Kaplan Sommer. Allison . Nobel Prize Winner George P. Smith Is a Longtime pro-Palestine, BDS Activist . . . 3 October 2018 . subscription . 4 October 2018 .
  12. Web site: Smith . George . George Smith . . United States . 16 June 2020 .
  13. Web site: George Smith. University of Missouri Biological Sciences . 3 October 2018 . dead . https://web.archive.org/web/20181003141349/http://biology.missouri.edu/people/?person=94#section-3 . Oct 3, 2018 .
  14. Web site: AAAS Fellows Share Nobel Prize in Chemistry. American Association for the Advancement of Science . 3 October 2018 . Andrea . Korte . live . https://web.archive.org/web/20231210103445/https://www.aaas.org/news/aaas-fellows-share-nobel-prize-chemistry . Dec 10, 2023 .
  15. Web site: Promega Biotechnology Research Award Past Laureates . American Society For Microbiology . 3 October 2018 . https://web.archive.org/web/20181003222437/https://www.asm.org/index.php/choma/140-awards-a-grants/past-laureates/7805-promega-biotechnology-research-award-past-laureates . 3 October 2018 . dead .
  16. News: Use of Evolution to Design Molecules Nets Nobel Prize in Chemistry for 3 Scientists . subscription . The New York Times . 3 October 2018 . 3 October 2018 . Chang . Kenneth . live . https://web.archive.org/web/20181003100611/https://www.nytimes.com/2018/10/03/science/chemistry-nobel-prize.html . 3 October 2018 .
  17. Web site: George P. Smith . National Academy of Sciences Member Directory . live . https://web.archive.org/web/20231204202442/https://www.nasonline.org/member-directory/members/20049500.html . Dec 4, 2023 .
  18. Web site: 2023 . Inaugural Mizzou Medal of Distinction awarded to George P. Smith in recognition of outstanding service // Show Me Mizzou // University of Missouri . 2023-10-11 . showme.missouri.edu . en-US.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "George Smith (chemist)".

Except where otherwise indicated, Everything.Explained.Today is © Copyright 2009-2024, A B Cryer, All Rights Reserved. Cookie policy.