| Gbôklé Region | |
| Native Name: | Région du Gbôklé |
| Native Name Lang: | fr |
| Settlement Type: | Region |
| Motto: | "Gbôklé, la plus belle Région de la Côte d’Ivoire" |
| Subdivision Type: | Country |
| Subdivision Type1: | District |
| Subdivision Name1: | Bas-Sassandra |
| Established Title: | Established |
| Established Date: | 2011 |
| Seat Type: | Regional seat |
| Seat: | Sassandra |
| Government Footnotes: | [1] |
| Leader Title: | Prefect |
| Leader Name: | Ernest Boni Koffi |
| Leader Title1: | Council President |
| Leader Name1: | Dakpa Philippe Legre |
| Unit Pref: | Metric |
| Area Footnotes: | [2] |
| Area Total Km2: | 6200 |
| Population Footnotes: | [3] |
| Population Total: | 460980 |
| Population As Of: | 2021 census |
| Population Density Km2: | auto |
| Timezone1: | GMT |
| Utc Offset1: | +0 |
Gbôklé Region is one of the 31 regions of Ivory Coast. Since its establishment in 2011, it has been one of three regions in Bas-Sassandra District. The seat of the region is Sassandra and the region's population in the 2021 census was 460,980.
Gbôklé is currently divided into two departments: Fresco and Sassandra.