| Garay Department | |
| Native Name Lang: | es |
| Settlement Type: | Department |
| Mapsize: | 180px |
| Pushpin Map Caption: | Location of Garay in Argentina |
| Coordinates: | -31.1°N -65°W |
| Subdivision Type: | Country |
| Subdivision Name: |  Argentina |
| Subdivision Type1: | Province |
| Subdivision Name1: | Santa Fe |
| Seat Type: | Head town |
| Seat: | Helvecia |
| Unit Pref: | Metric |
| Area Total Km2: | 3964 |
| Population Total: | 19913 |
| Population Density Km2: | auto |
| Timezone1: | ART |
| Utc Offset1: | -3 |
The Garay Department (in Spanish, Departamento Garay) is an administrative subdivision (departamento) of the province of Santa Fe, Argentina. It is located in the center-east of the province. It has about 20,000 inhabitants as per the . Its head town is the city of Helvecia (population 8,500). It is the least populated in the province.
Its neighbouring departments are San Javier in the north, San Justo in the west, and La Capital in the south. The eastern limit is marked by the Paraná River, which is the natural border with the province of Entre Ríos.
The towns and cities in this department are (in alphabetical order): Cayastá, Colonia Mascías, Helvecia, Saladero Mariano Cabal, and Santa Rosa de Calchines.