| Tradename: | Zactran |
| Dailymedid: | Gamithromycin |
| Routes Of Administration: | Subcutaneous |
| Class: | Macrolide antibiotic |
| Atcvet: | Yes |
| Atc Prefix: | J01 |
| Atc Suffix: | FA95 |
| Legal Us: | Rx-only |
| Legal Us Comment: | [1] [2] |
| Legal Eu: | Rx-only |
| Legal Eu Comment: | [3] [4] |
| Cas Number: | 145435-72-9 |
| Pubchem: | 59364992 |
| Drugbank: | DB11416 |
| Chemspiderid: | 28530824 |
| Unii: | ZE856183S0 |
| Kegg: | D06598 |
| Chebi: | 195437 |
| Chembl: | 2107342 |
| Synonyms: | ML-1709460, ML-460 |
| Iupac Name: | (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11--2-ethyl-3,4,10-trihydroxy-13--3,5,8,10,12,14-hexamethyl-7-propyl-1-oxa-7-azacyclopentadecan-15-one |
| C: | 40 |
| H: | 76 |
| N: | 2 |
| O: | 12 |
| Smiles: | [H][C@@]1(C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)O[C@H]1[C@H](C)[C@@H](O[C@]2([H])O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)N(CCC)C[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@@H]1C |
| Stdinchi: | 1S/C40H76N2O12/c1-15-17-42-21-22(3)33(44)40(11,48)29(16-2)52-36(46)26(7)32(53-30-20-39(10,49-14)34(45)27(8)51-30)25(6)35(38(9,47)19-23(42)4)54-37-31(43)28(41(12)13)18-24(5)50-37/h22-35,37,43-45,47-48H,15-21H2,1-14H3/t22-,23+,24+,25-,26+,27-,28-,29+,30-,31+,32-,33+,34-,35+,37-,38+,39+,40+/m0/s1 |
| Stdinchikey: | VWAMTBXLZPEDQO-UZSBJOJWSA-N |
Gamithromycin, sold under the brand name Zactran, is a veterinary medication used for the treatment of cattle, pigs, and sheep.[5] It is a macrolide antibacterial. It is a 7a-azalide.[6]
It was approved for veterinary use in the European Union in 2008.
In the EU, gamithromycin is indicated for the treatment and prevention of bovine respiratory disease in cattle, swine respiratory disease in pigs, and infectious pododermatitis (foot rot) in sheep.
In the US, gamithromycin is indicated for the treatment of bovine respiratory disease in cattle.