Galactosylceramide Explained

A galactosylceramide, or galactocerebroside is a type of cerebroside consisting of a ceramide with a galactose residue at the 1-hydroxyl moiety.

The galactose is cleaved by galactosylceramidase.

Galactosylceramide is a marker for oligodendrocytes in the brain, whether or not they form myelin.^{[1] [2]}

See also

• Alpha-Galactosylceramide
• Krabbe disease
• Myelin

External links

• • CHEMBL110111

Notes and References

1. 10.1038/274813a0 . Galactocerebroside is a specific cell-surface antigenic marker for oligodendrocytes in culture . Nature . 274 . 5673 . 813–816 . 1978 . Raff . Martin C. . Mirsky . Rhona . Fields . K. L. . Lisak . Robert P. . Dorfman . Susan H. . Silberberg . Donald H. . Gregson . N. A. . Leibowitz . Sidney . Kennedy . Mary C. . 355894 .
2. 10.1083/jcb.101.3.1135 . 3897245 . 2113740 . Galactocerebroside is expressed by non-myelin-forming Schwann cells in situ . The Journal of Cell Biology . 101 . 3 . 1135–1143 . 1985 . Jessen . K. R. . Morgan . L. . Brammer . M. . Mirsky . R. .