| Gagliano del Capo | |
| Official Name: | Comune di Gagliano del Capo |
| Shield Alt: | Coat of arms of Gagliano del Capo |
| Pushpin Label Position: | left |
| Coordinates: | 39.8431°N 18.3694°W |
| Province: | Lecce (LE) |
| Frazioni: | Arigliano and San Dana |
| Mayor: | Gianfranco Melcarne |
| Area Total Km2: | 16.6 |
| Population Total: | 4906 |
| Population As Of: | 1 January 2021 |
| Population Demonym: | Gaglianesi |
| Elevation M: | 144 |
| Saint: | Saint Roch |
| Day: | August 16 |
| Postal Code: | 73034 |
| Area Code: | 0833 |
Gagliano del Capo (Salentino: Sicilian: Gajànu[1]) is an Italian comune situated in the province of Lecce, the southernmost one of Apulia.
In its territory is located Ciolo, a rocky cove that is part of the Regional Natural Coastal Park of "Costa Otranto-Santa Maria di Leuca e Bosco di Tricase".