| Gadsden High School | |
| Established: | 1928 |
| Type: | Independent high school |
| Principal: | Maria Legarreta |
| Colors: | Maroon and gold |
| Athletics Conference: | NMAA, 5A Dist. 3 |
| Mascot: | Panther |
| Enrollment: | 1,471 (2016-17)[1] |
| Streetaddress: | 6301 Hwy 28 Las Cruces, New Mexico 88021 United States  |
| Website: | gisd.k12.nm.us |
Gadsden High School (GHS), originally named Valley High School, is a public high school in unincorporated Doña Ana County, New Mexico, United States, with an Las Cruces postal address. Gadsden High School is administered by Gadsden Independent School District.
Gadsden High School serves the surrounding towns of Mesquite, Vado, Berino, La Mesa, San Miguel, Chamberino, La Union, and Anthony.
The school's name is in reference to the land acquisition known as the Gadsden Purchase.
GHS competes in the New Mexico Activities Association (NMAA), as a class 6A school in District 3. State championships in football: 1953, 1954, 1955, 1961, 1962. (https://www.nmact.org/file/Football_Past_Champs.pdf)State championships in volleyball: 2010, 2011 (https://www.nmact.org/file/Volleyball_Champions.pdf)