| Gabriel Koyambounou | |
| Birth Place: | Bangui |
| Office: | Prime Minister of the Central African Republic |
| President: | Ange-Felix Patasse |
| Term Start: | 12 April 1995 |
| Term End: | 6 June 1996 |
| Predecessor: | Jean-Luc Mandaba |
| Successor: | Jean-Paul Ngoupandé |
| Party: | MLPC |
Gabriel Jean-Edouard Koyambounou (born 1947) is a Central African politician who was prime minister of the Central African Republic from 12 April 1995 to 6 June 1996. He is currently the first vice-president of the Movement for the Liberation of the Central African People (MLPC).
Koyambounou was acquitted of misuse of public funds on 6 December 2004.[1] After MLPC first vice-president Luc Dondon Apollinaire Konamabaye was suspended from his duties, Koyambounou, who was second vice-president, took over as first vice-president in an interim capacity in January 2006.[2]